SMBE2018 tweets from 10 July

NatureEcoEvo @NatureEcoEvo

Here are the H3K9 methylation studies that Kakutani is discussing: emboj.embopress.org/content/36/8/9… science.sciencemag.org/content/319/58… #SMBE2018

S. Lorena Ament @LoreAment

Tetsuji Kakutani: The epigenetic mark H3K9me1 affects gene body and TEs by removal of H3K4me1, which is always active in gene's enhancers. Many enhancers of mammals come from TEs themselves! #SMBE2018 #SMBE18

Dorota Paczesniak @DOPaczesniak

Looking forward to hearing the amazing early career scientists speak in Walter Fitch Symposium. What’s also great that it’s a plenary session so everyone can attend. #SMBE2018

Taraneh @taraneh_z

Excellent plenary by Tetsuji Kakutani about to be followed by the Fitch talks. Exciting morning at #SMBE2018 ! ☺️

23andMe Research @23andMeResearch

Super excited for the Fitch symposium to start! Always my favorite session at #SMBE2018

J.J. Emerson 🖥️ 🧬 @JJ_Emerson

Ana Marija Jaksic: Re-thinking a classic clinal trait: Pleiotropic consequences of thermally adaptive dopamine on pigmentation clines in Drosophila #SMBE2018 #FitchSymposium

Joshua G. Schraiber🌹 @jgschraiber

First up we have Ana Jaksic talking about pigmentation clines in drosophila. But opens up talking about spending grant money on cocaine ;-) #SMBE2018

Joshua G. Schraiber🌹 @jgschraiber

AJ: setting up an experimental evolution to see adaptation of flies to temperature over 100 generations. Then raised a common garden. What traits evolved? #SMBE2018

Marc RobinsonRechavi #IWillGetVaccinated 😷 @marc_rr

Ana Marija Jaksic kicks off Fitch symposium #SMBE2018 by explaining how she got her advisor to buy cocaine. twitter.com/merianelion/st…

Lionel Guy @LionelGuy

Now it's time for the Fitch symposium at #SMBE2018, where the rising stars of the society get the opportunity to talk. Ana Marija Jaksic @merianelion opens the session with this line: "This is how I convinced my PI to buy me cocaine.

23andMe Research @23andMeResearch

I had no idea dopamine was part of the chemical pathway to make melanin! Always learning something new #SMBE2018

Lionel Guy @LionelGuy

AJ: Dopamine pathway - part of the melanin pathway - upregulated in hot-treated Drosophila #SMBE2018

NatureEcoEvo @NatureEcoEvo

First in the Fitch Symposium is Ana Marija Jaksic on pigmentation differences between hot and cold experimentally evolved Drosophila populations. Pleiotropic effect of selection on dopamine pathway? #SMBE2018

Cedric 👾 Feschotte @CedricFeschotte

Arguably but predictably the best session of any SMBE meeting is the Walter Fitch Symposium #SMBE2018

Joshua G. Schraiber🌹 @jgschraiber

AJ: maybe it's actually dopamine that's selected. In fact, see that dopamine production enzymes are thermally adapted. Have a candidate transcription factor, and it seems to be thermally adapted #SMBE2018

Cheong Xin (CX) Chan @dorkyM

If you missed the boys last night, there's still a chance learn about genomics and evolution of dinoflagellates today and grab a poster printout at POA-021 and POA-024! #SMBE2018 @IMBatUQ #SMBE18 #dinoflagellates pic.twitter.com/RqrdR1Tan0

拡大

拡大

Chris Robles💀🧬 @ChrisOmics

Whats the best part of #SMBE2018? 1. The cutting edge research talks 2. The beautiful poster presentations 3. The japanese toilets

Joshua G. Schraiber🌹 @jgschraiber

AJ: new hypothesis: heat increases synaptic activity resulting in more dopamine signalling, this might be bad. Flies have evolved to optimize neuronal activity #SMBE2018

Joshua G. Schraiber🌹 @jgschraiber

AJ: lots of data to support hypothesis about mushroom body activity and dopamine as temperature adaptive #SMBE2018

J.J. Emerson 🖥️ 🧬 @JJ_Emerson

Mrudula Sane: Antagonistic pleiotropy is rare among new mutations #SMBE2018 #FitchSymposium

Joshua G. Schraiber🌹 @jgschraiber

Next up is Mrudula Sane discussing pleiotropy of new mutations. Antagonistic pleiotropy will alter fitness in opposite directions in different environments, i.e. tradeoffs #SMBE2018

NatureEcoEvo @NatureEcoEvo

Great to see free daycare provided at #SMBE2018 smbe2018.jp/childcare.html. See this recent article in @PNASNews for more recommendations on tackling the childcare-conference conundrum: pnas.org/content/early/…

Lionel Guy @LionelGuy

MS: Among beneficial mutations, AP is rare and fitness effects are not correlated. However, beneficial mutations are rare. So, how prevalent are AP among new mutations? #SMBE2018

Christian Landry @landrychristian

Mrudula Sunil Sane beautifully sets up her talk on antagonistic pleiotropy (AP) . Use MA lines in E. coli to show that AP is rare, althought pleiotropy is not rare #FitchSymposium #SMBE2018

Joshua G. Schraiber🌹 @jgschraiber

MS: in these mutations, AP is rare but variable across resources. But pleiotropy overall isn't that rare. What to expect under a null? Used resampling to get null expectation. Overall, AP is rarer than expected by chance #SMBE2018