Yeast 2011のまとめ
Beyond PPIs to prot-metabolite interact'ns: Probing prot-lipid interact'ns and specificities using lipid arrays http://bit.ly/pql2FM #ICYGMB
2011-07-16 18:26:08That concludes #ICYGMB 2011. Thanks to the organizers, speakers & attendees for a wonderful meeting. See you in Frankfurt in 2013!
2011-07-16 19:36:27That concludes #ICYGMB 2011. Thanks to the organizers, speakers & attendees for a wonderful meeting. See you in Frankfurt in 2013!
2011-07-16 19:36:27Space, the (final?) frontier: yeast deletion collection launched on Atlantis shuttle to study effect of microgravity on cell growth #ICYGMB
2011-07-16 19:32:32Automated HTP microscopy & SVMs to classify localiz'n of GFP collect'n to 16 diff locat'ns in cell for abundance localiz'n network. #ICYGMB
2011-07-16 19:23:39YeastKID: curated gold standard kinase interaction database: http://bit.ly/qu33jU used to score new kinase-substrate pairs from SDL #ICYGMB
2011-07-16 19:12:57Goal: Use genome-wide SDL screens to explore the yeast kinome. S. cerevisiae has 127 kinases & half of proteome is phosphorylated. #ICYGMB
2011-07-16 19:02:46All good things come to an end: B. Andrews about to give the closing lecture after a great week of science, fun & nature in Poland! #ICYGMB
2011-07-16 18:46:16New lipid binding domains found, ex. ECM25, has no LBD but has cryptic CRAL/TRIO domain previously undetected; PH domain in Pkh2 too #ICYGMB
2011-07-16 18:30:37Beyond PPIs to prot-metabolite interact'ns: Probing prot-lipid interact'ns and specificities using lipid arrays http://bit.ly/pql2FM #ICYGMB
2011-07-16 18:26:08AC Gavin on M. pneumoniae as a new model organism - small minimal genome ideal for determining a molecular anatomy of a cell #ICYGMB
2011-07-16 18:18:09Evol'n is so cool! Oliver: orthologs of S.cere haploinsuff genes underrepresented on animal X chromos that do X-chromo inactivation #ICYGMB
2011-07-16 17:33:23S.Oliver: orthologs of S.cerevisiae haploinsufficiency genes retained across Fungi, overrepresented on mating-type chromosomes #ICYGMB
2011-07-16 17:21:08Can you say 'phosphoproteomics'? Steve Oliver: no. of P'n sites on a protein is determinant of gene retention after whole-genome dup #ICYGMB
2011-07-16 17:12:07Can you say 'phosphoproteomics'? Steve Oliver: no. of P'n sites on a protein is determinant of gene retention after whole-genome dup #ICYGMB
2011-07-16 17:12:07Whew! glabrata cbk1 null is hypervirulent, clumpiness means cannot be phagocytosed by macrophages, BUT, is also drug-hypersensitive #ICYGMB
2011-07-16 17:06:15Transceptors (Gap1,Pho84,Mep2,etc) are signaling pathway receptors that evolved from transporters and still perform both functions #ICYGMB
2011-07-16 00:04:46Johan Thevelein (Leuven) reviews general nutrient signaling pathways that act through PKA on transceptors, such as Pma1, in PM #ICYGMB
2011-07-15 23:47:59R.Haguenauer-Tsapis: how Rsp5 ubiquitin ligase finds Jen1 in the PM? Arrestin Art4 does the arrest in response to glucose #ICYGMB
2011-07-15 23:28:31D.Drubin marvels at actin's multiple personalities: 1 actin in 1 cytoplasm forms 3 filament systems; the twist is what may matter #ICYGMB
2011-07-15 22:59:57Keep your eyes open, folks! Good reminder from David Drubin: the unexpected things that one sees are really the most exciting #ICYGMB
2011-07-15 22:49:33David Drubin (UC Berkley): Bzz1 & Rvs161/7 are required for normal geometry of endocytic vesicles #ICYGMB
2011-07-15 22:48:04K.Ayscough from UK starts off the Intracellular Traffic plenary session: Vps1 works with Rvs167 to choreograph endocytic scission #ICYGMB
2011-07-15 22:28:49Akira Kaji: inhibiting the ribosome recycling step; eEF3 - an ideal target for anti-fungal drug as it is not conserved in mammals #ICYGMB
2011-07-15 20:09:05JJ Garcia-Gomez talks about the roll of Spb4 in processing of 27SB pre-rRNA and biogenesis of the 60S ribosomal subunit. #ICYGMB
2011-07-15 19:44:24