小児甲状腺乳頭がんの治療:放射線療法は必要ないという意見

Hay ID. (2010): Long-Term Outcome in 215 Children and Adolescents with Papillary Thyroid Cancer Treated より
2
kazu @Kazu031104

Hay ID. (2010) "Long-Term Outcome in 215 Children and Adolescents with Papillary Thyroid Cancer Treated ..." http://t.co/BjBegSilh4

2013-04-29 09:40:26
kazu @Kazu031104

@myen Hay (2010) ".. younger than 21 years of age at initial PTC diagnosis, .. during a 68-year period between .. 1940 and .. 2008, .."

2013-04-29 09:42:53
kazu @Kazu031104

@myen Hay (2010) "All relevant histologic slides were reexamined and reclassified according to current WHO criteria ..."

2013-04-29 09:43:22
kazu @Kazu031104

@myen Hay (2010) ".. were treated within 60 days of the initial diagnosis."

2013-04-29 09:44:22
kazu @Kazu031104

@myen Hay (2010) "Two hundred fifteen (99%) of the 218 patients gave consent to participate in the follow-up study ..."

2013-04-29 09:45:07
kazu @Kazu031104

@myen Hay (2010) "Death certificates were examined for the 22 patients (10%) who were known to have died."

2013-04-29 09:45:49
kazu @Kazu031104

@myen Hay (2010) "The median follow-up of the 215 patients was 28.7 years (range = 0.6–64.5 years)"

2013-04-29 09:46:35
kazu @Kazu031104

@myen Hay (2010) "Death was due to PTC in two (0.9%) cases."

2013-04-29 09:47:01
kazu @Kazu031104

@myen Hay (2010) "The median age at diagnosis of PTC was 16 years (range = 3–20 years)."

2013-04-29 09:48:46
kazu @Kazu031104

@myen Hay (2010) "In 36 patients (17%), there was a prior history of head or neck irradiation, which occurred during 1936 through 1957."

2013-04-29 09:49:14
kazu @Kazu031104

@myen Hay (2010) "The mean tumor size was 2.65 cm in maximum diameter (median = 2.20 cm; range = 0.1–9.5 cm)."

2013-04-29 09:49:51
kazu @Kazu031104

@myen Hay (2010) "Tumors were demonstrated to be multicentric in 29% of 190 examined specimens."

2013-04-29 09:50:50
kazu @Kazu031104

@myen Hay (2010) "39 (18%) of the primary tumors at presentation were locally invasive to extrathyroidal soft tissues"

2013-04-29 09:51:41
kazu @Kazu031104

@myen Hay (2010) "12 (6%) had distant metastases found no later than 30 days after the date of the initial surgical procedure"

2013-04-29 09:52:21
kazu @Kazu031104

@myen Hay "167 (78%) had metastatic involvement of regional lymph nodes at the time of initial surgery (60% had 4 or more metastatic nodes)"

2013-04-29 09:53:16
kazu @Kazu031104

myen Hay (2010) "Bilateral lobar resection (BLR) was performed in 188 (87%) juvenile PTC patients during the period of study."

2013-04-29 09:53:52
kazu @Kazu031104

@myen Hay (2010) ".. near-total thyroidectomy (NTT), which accounted for 96 (45%) of the initial operations."

2013-04-29 09:54:53
kazu @Kazu031104

@myen Hay (2010) "Total thyroidectomy (TT) was the second most popular operation and was performed in 82 cases (38%)."

2013-04-29 09:55:34
kazu @Kazu031104

@myen Hay (2010) "Unilateral lobectomy (UL) was .. in 25 cases (12%); lesser procedures were performed in the remaining 1%."

2013-04-29 09:56:43
kazu @Kazu031104

@myen Hay (2010) "Bilateral subtotal thyroidectomy (BST) was performed in only 10 cases (5%)."

2013-04-29 09:57:08
kazu @Kazu031104

@myen Hay "Permanent unilateral recurrent laryngeal nerve damage .. in 12% after UL, in 0% after BST, in 6% after TT, and in 2% after NTT."

2013-04-29 09:59:03
kazu @Kazu031104

@myen Hay (2010) "Permanent hypoparathy- roidism ... occurred in none of the 35 patients who had either a UL or a BST."

2013-04-29 10:00:13
kazu @Kazu031104

@myen Hay (2010) ".. permanent hypoparathyroidism resulted in 4% after NT and in 29% after TT. "

2013-04-29 10:00:43
kazu @Kazu031104

@myen Hay (2010) "During 1950–1979, 22 of 43 ..(in) TT (51%) .. permanent hypoparathyroidism, whereas since 1980, only 2 of 30 (5%) ..."

2013-04-29 10:02:38
kazu @Kazu031104

@myen Hay (2010) "One hundred eighty-five (86%) of the PTC patients underwent removal of neck nodes as part of the initial operation."

2013-04-29 10:04:04