posts aggrigation for "The biology of genomes" (2)
Mixed social media review for #bg2011: tweeters very eager to share, even promoting posters! some speakers won't allow coverage...
2011-05-13 22:27:17I'm #ff 'n the #bg2011 tweeters, @dgmacarthur @assemblathon @lukejostins @genome_gov @luke_ward Thanks for letting me be there a bit.
2011-05-13 22:35:05That was a great talk on human/neanderthal evolution. Sorry we couldn't cover that via twitter #bg2011
2011-05-13 22:36:54The last talk was by S Pääbo @ #BG2011, also NOT Tweetable, but he's published much
2011-05-13 22:37:40A lot of the material covered in the last talk is covered by a great Wikipedia page on Denisovans http://t.co/MQvP6Ta #bg2011
2011-05-13 22:39:31#bg2011 Anjali Gupta Hinch is up now. Non-tweetable
2011-05-13 22:41:53While we can't tweet Neanderthal talks, check out this somewhat controversial piece on Neanderthal dating: http://bit.ly/j7R2bC #bg2011
2011-05-13 22:41:56Third talk that is a David Reich collaboration #bg2011
2011-05-13 22:42:15Admixture in African Americans (w D Reich) is also not Tweetable @ #BG2011
2011-05-13 22:43:39Tweeting from Cold Spring Harbor Biology of Genomes Meeting. Talk #3 by Anjali Hinch re.recombination in humans - untweetable. #bg2011
2011-05-13 22:44:51Drive against hotspot motifs in primates implicates PRDM9 gene in meiotic recombination http://www.ncbi.nlm.nih.gov/pubmed/20044541 #BG2011
2011-05-13 22:46:03#bg2011 Roger Pique-Regi is up next for a tweetable talk on SNPs, chromatin accessibility and gene expression variation
2011-05-13 22:57:07Roger Pique-Regi:SNPs, chromatin accessibility and expression #bg2011
2011-05-13 22:57:43Roger Pique-Regi: SNPs affecting chromatin accessibility: important contributors to gene expression variation (Pritchard/Gilad labs) #bg2011
2011-05-13 23:00:22#bg2011 RP: want to understand how genetic variation gets linked to gene expression differences in humans
2011-05-13 23:00:57#bg2011 RP: goal: understand molecular mechanisms linking genetic variation to gene expression differences (eQTLs)
2011-05-13 23:00:59Roger Pique-Regi: SNPs that influence expression via chromatin #bg2011
2011-05-13 23:01:31#bg2011 RP: DNA-binding proteins are an important part of his process. We focus on chromatin accessibility via DNase-seq
2011-05-13 23:01:47#bg2011 RP: Looking at DNA binding proteins that might affect chromatin accessibility in particular
2011-05-13 23:01:51First tweetable talk of the session is from Roger Pique-Regi, on the genetics of chromatin accessibility. #bg2011
2011-05-13 23:02:03Cited paper on finding DNase footprints with dynamic Bayesian networks (uses Segway) http://www.ncbi.nlm.nih.gov/pubmed/20529925 #bg2011
2011-05-13 23:02:39#bg2011 RP: Use DNA-seq to measure 'footprints' of regions which might be bound by transcription factors
2011-05-13 23:03:00#bg2011 RP: 70 YRI lymphoblastoid cell lines (LCLs). 44.2 Mreads/sample with genotype info from G1K and HapMap
2011-05-13 23:03:50#bg2011 RP: Used 70 cell lines, 44.2 million reads per sample, 1000 genomes & HapMap info, RNA-seq expression data, and ENCODE data
2011-05-13 23:03:56