小児甲状腺乳頭がんの治療：予後因子
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Seiichi Ushikubo
@sushikubo
@myen ItoY. (2012) "Prognosis and prognostic factors of papillary thyroid carcinoma in patients under 20 years" https://t.co/lVdq6SsX
2013-02-20 20:04:16It is therefore suggested that high-dose RAI administration immediately after surgery should be avoided and routine total thyroidectomy is not mandatory for patients with no aggressive features.
In summary, we demonstrated that aggressive characteristics such as distant metastasis at diagnosis, a large tumor size, and large node metastasis were frequently detected in PTC patients younger than 20 years, although significant extrathyroid extension was not. Node metastasis 3 cm or larger and an age of 16 years or younger independently predict a poor LN-RFS, and node metastasis 3 cm or larger and significant extrathy- roid extension were independent prognostic factors for DRFS.
In our series, 51 patients did not undergo total thyroidectomy at the initial surgery. Of these, only 2 (4%) showed recurrence to the remnant thyroid. Furthermore, none of the M0 patients in our series underwent high- dose RAI administration immediately after the initial surgery.
Seiichi Ushikubo
@sushikubo
@myen Ito (2012): Table1 Difference in clinicopathological features between M0 and M1 PTC patients under 20 years(%) http://t.co/yo2aOrWA
2013-02-20 20:11:05
拡大
Seiichi Ushikubo
@sushikubo
@myen Ito (2012): Fig. 1 LN-RFS of 101 PTC patients under 20 years. http://t.co/QycRbuVW
2013-02-20 20:12:11
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Seiichi Ushikubo
@sushikubo
@myen Ito (2012): Fig. 2 DRFS of 101 PTC patients under 20 years. http://t.co/N9o9jqvE
2013-02-20 20:13:17
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Seiichi Ushikubo
@sushikubo
@myen Ito (2012): Table 2 Uni- and multivariate analyses for LN-RFS of 102 patients under 20 years. http://t.co/zaSaAqrO
2013-02-20 20:14:36
拡大
Seiichi Ushikubo
@sushikubo
@myen Ito (2012): Table 3 Uni- and multivariate analyses for DRFS of 102 patients under 20 years http://t.co/25VBy5NT
2013-02-20 20:15:35
拡大
Seiichi Ushikubo
@sushikubo
@myen Ito (2012): "aggressive characteristics such as distant metastasis at diagnosis, a large tumor size, and large node metastasis ..."
2013-02-20 20:18:31
Seiichi Ushikubo
@sushikubo
@myen Ito (2012) "... were frequently detected in PTC patients younger than 20 years"
2013-02-20 20:19:09
Seiichi Ushikubo
@sushikubo
@myen Ito (2012) "Node metastasis 3 cm or larger and an age of 16 years or younger independently predict a poor LN-RFS,"
2013-02-20 20:20:25
Seiichi Ushikubo
@sushikubo
@myen Ito (2012) "node metastasis 3 cm or larger and significant extrathy- roid extension were independent prognostic factors for DRFS"
2013-02-20 20:21:15
Seiichi Ushikubo
@sushikubo
@myen Ito (2012) "51 patients did not undergo total thyroidectomy at .. initial surgery. .. only 2 (4%) .. recurrence to .. remnant thyroid"
2013-02-20 20:24:59
Seiichi Ushikubo
@sushikubo
@myen Ito (2012) "high-dose RAI administration immediately after surgery should be avoided ..."
2013-02-20 20:27:01
Seiichi Ushikubo
@sushikubo
@myen Ito (2012) "... and routine total thyroidectomy is not mandatory for patients with no aggressive features."
2013-02-20 20:27:43