小児の甲状腺がん
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- いいね！2
Seiichi Ushikubo
@sushikubo
@myen Wartofsky ref-11: Vander J. "The significance of nontoxic thyroid nodules ..." Ann Intern Med 1968; 69:537–540 http://t.co/FqQu0ojM
2013-02-20 20:59:20During the 15-year period of observation, 67 new lesions were detected in persons previously found to be free of thyroid disease. This represented a 15-year incidence rate of 1.4%, 1.7% in females and 0.9% in males. None of these newly detected lesions showed evidence of malignancy.
(有料論文のためアブストラクトのみ)
解剖所見では50%の人に甲状腺結節が存在するが、その多くは小さい
超音波検査では70％の成人に甲状腺結節が存在するが、そのほとんどが小さく、臨床意義ははっきりしない
Seiichi Ushikubo
@sushikubo
@myen Wartofsky (2006) "Although autopsy studies indicate thyroid nodules in as many as 50% of consecutive necropsies, ..."
2013-02-20 21:01:34
Seiichi Ushikubo
@sushikubo
@myen Wartofsky (2006) "... many may be small and clinically inapparent"
2013-02-20 21:02:19
Seiichi Ushikubo
@sushikubo
@myen Wartofsky (2006) "Indeed, nodules may be detected by ultrasound in up to 70% of adults, ..."
2013-02-20 21:04:09
Seiichi Ushikubo
@sushikubo
@myen Wartofsky (2006) "... but most will be quite small and of uncertain clinical importance."
2013-02-20 21:04:59
Seiichi Ushikubo
@sushikubo
@myen Wartofsky (2006) "a discrepancy exists between the true prevalence of thyroid nodules and that seen by physical exam."
2013-02-20 21:06:04結節の大きさが1cmあれば、触って判る
Seiichi Ushikubo
@sushikubo
@myen Wartofsky (2006) "nodules must approach 1 cm in diameter to be recognized on palpation."
2013-02-20 21:07:25触って判る大きさの甲状腺結節の10-14%が甲状腺がん
Seiichi Ushikubo
@sushikubo
@myen Wartofsky (2006) "Cancers are found in 10–14% of patients presenting with palpable thyroid nodules."
2013-02-20 21:21:46
Seiichi Ushikubo
@sushikubo
@myen Wartofsky (2006) "Most true intrathyroidal nodules will represent colloid adenomas (27–60%) or simple follicular adenomas (26–40%)."
2013-02-20 21:22:56解剖された人の6%に甲状腺がんがある
Seiichi Ushikubo
@sushikubo
@myen Wartofsky (2006) "Autopsy studies have revealed occult thyroid cancer in 6% of autopsies in North American series (25)."
2013-02-20 21:24:23
Seiichi Ushikubo
@sushikubo
@myen Wartofsky ref-25: Sampson RJ. "Occult thyroid carcinoma in Olmsted County, ..." Cancer 1974; 34:2070–2076 http://t.co/c7cbLQrX
2013-02-20 21:28:47「小さく触れる事のできない乳頭がんは臨床的に重要でない」というのが一般的な合意である。
Seiichi Ushikubo
@sushikubo
@myen Wartofsky"There is general agreement that these small, occult, and mostly papillary cancers are of little or no clinical significance"
2013-02-20 21:30:29Merrily Poth 小児の甲状腺がん
Seiichi Ushikubo
@sushikubo
@myen Merrily Poth "Thyroid Cancer in Children and Adolescents." In: Wartofsky L. Thyroid cancer: a comprehensive guide to clinical manage..
2013-02-20 21:39:2521歳以下での甲状腺がんの "indicence" は、100,000人に1~6人。
Seiichi Ushikubo
@sushikubo
@myen Poth (2006) "The incidence of thyroid cancer varies from 1 to 6 per 100,000 individuals under the age of 21"
2013-02-20 21:40:54