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uchida_kawasaki
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Seiichi Ushikubo
@sushikubo
@myenSU "... incidence of which rapidly increases during the third decade of life and is 3 times as common in women, ..."
2014-11-16 22:59:57
Seiichi Ushikubo
@sushikubo
@myenSU "... suggest that BRAF- and RAS-positive tumors found in this cohort were likely to develop ..."
2014-11-16 23:00:52
Seiichi Ushikubo
@sushikubo
@myenSU "... via pathogenic mechanisms more typical of sporadic thyroid cancer."
2014-11-16 23:01:04
Seiichi Ushikubo
@sushikubo
@myenSU Leeman-Neill (2013) "this study provides strong support for the association between .. rearrangements and exposure to 131I ..."
2014-11-16 23:05:04
Seiichi Ushikubo
@sushikubo
@myenSU ".... with high .. doses, we hypothesize that undiscovered .. events important in radiation-induced .. carcinogenesis must exist."
2014-11-16 23:07:59
Seiichi Ushikubo
@sushikubo
Tuttle RM (2008) "ret/PTC Activation Is Not Associated with Individual Radiation Dose ..." ncbi.nlm.nih.gov/pmc/articles/P…
2014-11-16 23:11:38
Seiichi Ushikubo
@sushikubo
@myenSU Tuttle RM (2008) Table 2. Characteristics of 100 Patients with ... Childhood: Ret/PTC1 3例, Ret/PTC3 2例 pic.twitter.com/14dUbfakh0
2014-11-16 23:16:36
拡大
Seiichi Ushikubo
@sushikubo
@myenSU Tuttle RM (2008) Table 3. ret/PTC Activation by Demographic Characteristics pic.twitter.com/9sBHitHFBg
2014-11-16 23:25:48
拡大
スカルライド
@skull_ride
年齢ごとに調べると「RET/PTCは小児に、BRAFは成人に多く、放射線には無関係という傾向がある」という事だと思います。それ以上の事はちょっと分からないですね。成長速度には当然影響あると思いますが••RT @iPatrioticmom: 成長速度によって発症or発見時期が違う？
2014-11-17 07:53:33
Seiichi Ushikubo
@sushikubo
Xing M (2014) "Association Between BRAF V600E Mutation and Recurrence of Papillary Thyroid Cancer" jco.ascopubs.org/content/early/…
2014-11-17 08:08:48
Seiichi Ushikubo
@sushikubo
知っているから、堂々と学会発表しているんだと思うけど。 BRAF陽性ならば、将来の何処かの時点で、手術をすることになる可能性が高いと判断されるわけだから。
2014-11-17 22:22:55
iPatrioticmom
@iPatrioticmom
↓ RET/PTCのほうは被曝量相関なくてBRASorRASのほうはマイナス相関に見えるけど、62例だけだし、調査時期によっては早く発症するタイプは発症しちゃった後だったりしないのかな。
2014-11-17 22:27:42
Seiichi Ushikubo
@sushikubo
これは、どうなんだろう。 twitter.com/sushikubo/stat… twitter.com/sushikubo/stat… twitter.com/sushikubo/stat…
2014-11-17 22:30:23
Seiichi Ushikubo
@sushikubo
@myenSU ICRP Draft Report "the most common point mutation in the BRAF gene, ..."
2014-11-14 23:36:22
Seiichi Ushikubo
@sushikubo
@myenSU "... although it is not the major event in childhood thyroid cancer after the Chernobyl accident, involves T:A to A:T transversion,"
2014-11-14 23:37:11
Seiichi Ushikubo
@sushikubo
@myenSU "... which could not be the transversion induced by oxidative DNA damage."
2014-11-14 23:37:35
Yuri Hiranuma
@YuriHiranuma
知らないのかも・・ 抄録は8月に出てたし。この論文は10月のだし。狸だし。 jco.ascopubs.org/content/early/…
2014-11-17 22:33:48
Yuri Hiranuma
@YuriHiranuma
@PriamalFear にゃ ありがとございます。2ページw thyroid.org/wp-content/upl…
2014-11-17 23:14:27
Priamal Fear
@PriamalFear
@YuriHiranuma 本体9頁 つ jama.jamanetwork.com/article.aspx?a…
2014-11-17 23:22:22
Yuri Hiranuma
@YuriHiranuma
@PriamalFear この2つ、タイトルは違うだすね。まあ、情報自体は2013年に出てたとして、医大でもわかってるはずだと想定できるだすが。 jama.jamanetwork.com/article.aspx?a… thyroid.org/wp-content/upl…
2014-11-18 08:21:36