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- いいね！0
UNSCEAR 2010 Report: "Summary of low-dose radiation effect on health"
http://www.unscear.org/docs/reports/2010/UNSCEAR_2010_Report_M.pdf
Seiichi Ushikubo
@sushikubo
@myen UNSCEAR 2010. p14. (44) In 2006, the Committee also provided an assessment of the effects of ionizing radiation on the immune system.
2012-08-12 11:24:55
Seiichi Ushikubo
@sushikubo
@myen UNSCEAR 2010 p14 (44) In principle, if radiation served to enhance or diminish the capacity of the body to mount an immune response ..
2012-08-12 11:26:16
Seiichi Ushikubo
@sushikubo
@myen UNSCEAR 2010 p14 .. to an infection, cancer or other disease, the risk of any disease due to radiation exposure could be affected.
2012-08-12 11:27:16
Seiichi Ushikubo
@sushikubo
@myen UNSCEAR 2010 p14. While many studies were examined, it remained impossible to make a clear judgement ...
2012-08-12 11:28:47
Seiichi Ushikubo
@sushikubo
@myen UNSCEAR 2010. p14. ... as to whether the effects on the immune system of radiation at low doses served to stimulate or suppress imm ..
2012-08-12 11:31:34
Seiichi Ushikubo
@sushikubo
@myen UNSCEAR 2010 p14. ... to whether the effects ... of radiation at low doses served to stimulate or suppress immune responses.
2012-08-12 11:32:52(多くの研究がされているが、低線量での放射線の影響で、免疫反応が刺激されるのか、あるいは、抑制されるのかは、はっきりしていない)
UNSCEAR 2006 REPORT: "EFFECTS OF IONIZING RADIATION" Annex D: Effects of ionizing radiation on the immune system
http://www.unscear.org/docs/reports/2006/09-81160_Report_Annex_D_2006_Web.pdf
INTRODUCTION
3. The scope of this annex includes reviews of:
− Radiation-induced alterations of the immune response, including immunosuppression (depression) or immunostimulation (activation);
− Possible mechanisms by which the immune system is altered following exposure to ionizing radiation;
− Epidemiological assessments of immune system alterations in various diseases, with emphasis on the effects of ionizing radiation.
1 放射線が誘導する免疫系の変化（免疫系の抑制と活性化）
2 免疫系が変化するメカニズム
3 免疫系の変化についての疫学的な評価
VII. CONCLUDING REMARKS
(466) At low doses and dose rates, the effects of ionizing radiation on the immune system may be suppressive or stimulatory. The long-term impact of low radiation doses on the immune function in relation to human health needs to be further evaluated.
(低線量・低線量率の領域では、放射線は、免疫系を抑制するかもしれないし、刺激するかもしれない。長期間の低線量被ばくと健康との関連については、さらに検討を要する）
V. FINAL SUMMARY
450. The effects of ionizing radiation on the immune system at low doses (<200 mGy) and low dose rates (<100 mGy/h) remain controversial.
451. In atomic bombing survivors and the residents of Techa riverside villages, the haematolymphoid system was damaged in a dose-dependent manner, although the groups underwent different types of radiation exposure. Several months or even years later, their systems regenerated, and haematolymphoid function recovered almost completely. However, even after several decades, with different effects in the two populations, significant effects have been observed in the haematolymphoid systems.
452. In atomic bombing survivors, ...
453. In Techa riverside village populations ...
456. Epidemiological findings suggest that the radiation- induced impairment of immunocompetence may increase the risk of diseases that normally occur in elderly people.
457. A statistically significant dose–response relationship has been found for several inflammatory biomarkers in irra- diated subjects. The persistent inflammatory status induced by ionizing radiation may increase the risks of both cancer and non-cancer diseases.
I. GENERAL FEATURES OF THE IMMUNE SYSTEM
II. RADIATION-INDUCED ALTERATIONS OF THE IMMUNE SYSTEM
III. POSSIBLE MECHANISMS INVOLVED AND IMPLICATIONS
Seiichi Ushikubo
@sushikubo
@myen UNSCEAER 2006. ANNEX D. III. POSSIBLE MECHANISMS INVOLVED AND IMPLICATIONS.
2012-08-12 13:43:38