HMP2010-09-01
Petrosino: first need to characterize next gen seq before integrating into metagenomic studies #HMP2010
2010-09-02 00:33:28Petrosino: used mock community to look at biases in sequencing #HMP2010
2010-09-02 00:35:02Petrosino: GAII vs. HiSeq data comparison with 35 HMP samples #HMP2010
2010-09-02 00:40:20Petrosino: 'feeling pretty good about HiSeq' #HMP2010
2010-09-02 00:40:47Petrosino: assembling WGS data - lose granularity of sample and QC is difficult #HMP2010
2010-09-02 00:42:01Petrosino: Herpes threatening Asian elephants; Baylor helping due to loss of elephants at Houston zoo #HMP2010
2010-09-02 00:51:39Petrosino: HiSeq compares well with GAII data, viral protocols improving, metagenomic techniques can help determine causes of dz #HMP2010
2010-09-02 00:53:12Joe Petrosino from Baylor giving overview of role of Baylor in HMP #HMP2010
2010-09-02 00:31:19Petrosino - reminds people that not only is HMP producing data and science, but also spin off benefits akin to space program #HMP2010
2010-09-02 00:32:15Petrosino: key ?s: what are biases, how do new sequencing platforms perform, what is gained/lost from assemblies #HMP2010
2010-09-02 00:33:42Petrosino has interesting results on sequencing mock community, I note we have study like this in PLoSone http://bit.ly/cPaIKF #HMP2010
2010-09-02 00:39:57Petrosino doing some interesting analysis of the risks/benefits of assembly in metagenomics #HMP2010
2010-09-02 00:43:17Note of caution: For statement "X manipulations of microbes help treat X ailments in X people X of the time": X="some" NOT "all" #HMP2010
2010-09-02 00:46:04Petrosino working on a viral metagenomic sequencing pipeline including isolation, concentration strategies #HMP2010
2010-09-02 00:47:48Microblogging Joseph Petrosino's talk http://ff.im/q38kE #HMP2010
2010-09-02 00:30:42#HMP2010 Re Petrosino talk, I wonder what Q-scores are for Hi-Seq assemblies vs GA-II. Maybe that's why contig is smaller?
2010-09-02 00:47:12Now Phil Tarr from @wustl on infant microbiome and necrotizing enterocolitis #HMP2010
2010-09-02 00:53:54Tarr: necrotizing enterocolitis is under-appreciated disease that occurs in premies; not well-publicized #HMP2010
2010-09-02 00:54:46Tarr: 7-12% of premies have necrotizing enterocolitis (NEC) with 20-30% fatality rate #HMP2010
2010-09-02 01:00:40Tarr: hypothesis: enteric biomass (incl bacteria & viruses) associated with cause of NEC #HMP2010
2010-09-02 01:01:52Tarr: "massively parallel stool collection. all stools all the time" #HMP2010
2010-09-02 01:04:16Tarr: increase in fecal mRNA pro-inflammatory transcripts in stool at least a day in advance of NEC onset #HMP2010
2010-09-02 01:11:40Next up - Philip Tarr on the infant microbiome and necrotizing einterocolitis #HMP2010
2010-09-02 00:54:50I have created a PaperLi newspaper on the human microbiome meeting tweets - see http://www.paper.li/tag/HMP2010 #HMP2010
2010-09-02 00:57:50Phil Tarr telling a very sad story of a premature infant dying of necrotizing enterocolitis - which is alas very common #HMP2010
2010-09-02 01:00:21