@myen Matsuse (2012) "The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma .." http://t.co/dOemdjbpzp
2013-06-30 01:37:24MAPK signaling pathway の遺伝子異常
@myen Ciampi (2007): FIG. 1. Schematic representation of the MAPK signaling pathway http://t.co/OXzgl2Iszk
2013-07-05 11:04:44ooooooooooooooooooooooooooooooooo
チェルノブイリ小児甲状腺がんとRET/PTC再構成
発症までの期間と遺伝子異常の種類には相関がある
RET/PTC再構成を伴っていると、発症までの期間が短くなる
@myen Hartmut M. (2000) Pattern of Radiation-induced RET and NTRK1 Rearrangements .. http://t.co/aLUzh4ua
2012-10-07 10:23:58@myen Hartmut (2000) Fig3 "ELE1/RET .. speed up progression not only .. rearrangement-negative, but also .. H4/RET .." http://t.co/7kr6NSEd
2012-10-07 13:42:11@myen Hartmut M. (2000) Fig. 1: Prevalence of gene rearrangements as a function latency period. http://t.co/9eEZzODr
2012-10-07 13:52:07原爆被爆者でのRET/PTC再構成
原爆被爆者でも、発症までの期間が短い人にRET/PTC再構成が多い
Hamatani K (2008) "RET/PTC Rearrangements Preferentially Occurred in Papillary Thyroid Cancer among Atomic Bomb ..." http://t.co/Dip3DgTwqS
2013-05-17 16:05:58@myen Hamatani (2008): Figure 1. relative frequency of RET/PTC and BRAF-V600E alterations in PTC patients http://t.co/AmJIgjq660
2013-05-17 17:49:54ooooooooooooooooooooooooooooooooo
放射線関連小児甲状腺がんと散発性小児甲状腺がんとの臨床的類似性
小児甲状腺がんの特徴:
放射線関連小児甲状腺がんと散発性小児甲状腺がんの臨床像は似ている
原因によらず臨床像/予後は成人の甲状腺癌とは異なる
Clinical Presentation and Clinical Outcomes in Chernobyl-related Paediatric Thyroid Cancers. Tuttle R.M. et.al. 2011. http://t.co/bpjsaRoF
2012-09-17 00:29:50@myen Tuttle R.M. et.al. Clinical Oncology 23 (2011) 268-275. Table 4. Summary data ... http://t.co/bpjsaRoF http://t.co/Ji0tzKZP
2012-09-17 00:54:10Tuttle (2011) Talbe 1. Initial presenting features and primary clinical outcomes http://t.co/60leaA2j
2013-02-14 18:43:30Tuttle RM. (2011) Table 3 paediatric, non-radiation-related differentiated thyroid cancers http://t.co/fWDRa73T
2013-02-14 18:49:32ooooooooooooooooooooooooooooooooo
放射線関連小児甲状腺がんと散発性小児甲状腺がん ー 臨床像と遺伝子異常の関係について