posts aggrigation for "The biology of genomes" (1)
in yeast, AA sub rate varies with the set of chaperones that the encoded protein uses.. as does expression level (all 3 correlated) #bg2011
2011-05-13 11:33:49TD: chaperone sequence evo correlates with protein expression #bg2011
2011-05-13 11:33:56Pavel Tomancak: "Gene expression divergence recapitulates the develpomental hourglass" #bg2011
2011-05-13 11:37:55PT: cf ontogeny recapitulates phylogeny #bg2011
2011-05-13 11:42:28PT: Darwins expln for the similarity of fetuses x-species - the fetus is shielded from the environment, #bg2011
2011-05-13 11:43:31PT: morphology starts divergent,similar @ phylotypic stage of devel,then diverges again. Does expression go through hourglass too? #bg2011
2011-05-13 11:46:20PT: variation in expression is higher 'early' and 'late' in development than in 'middle'; similar to morphology #bg2011
2011-05-13 11:50:26PT: evidence of stabilizing selection in maintenance of the pattern of expression variation #bg2011
2011-05-13 11:53:12Glad I stayed for Pavel Tomancak's wonderful late-nite #bg2011 talk on gene expression recapitulating the developmental hourglass!
2011-05-13 11:53:50PT: ancient genes of multicellularity are expressed at the least divergent stage of development #bg2011
2011-05-13 11:55:02PT: Also genes expressed at the phylotypic stage are evolutionarily more ancient #bg2011
2011-05-13 11:55:20Good night from Cold Spring Harbor #bg2011
2011-05-13 11:55:31Yay! RT @lukejostins: KB: Which assembly was best? Everyone is a winner but SOAPdenovo, ALLPATHS and SGA were more winners than most #BG2011
2011-05-13 13:11:27Call THAT a title?!?! :-) “@dgmacarthur: Aoife McLysaght (@aoifemcl) ancient duplicated genes and human disease. #bg2011”
2011-05-13 15:54:12