posts aggrigation for "The biology of genomes" (1)

meeting page is http://meetings.cshl.edu/meetings/genome11.shtml . tweets searched by #bg2011 at 2011-05-14, RTs & duplicates are removed by the function of togetter. free to edit. please see http://togetter.com/li/136669 for posts later than 2011-05-13 15:54:12.
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Luke Ward @Luke__Ward

in yeast, AA sub rate varies with the set of chaperones that the encoded protein uses.. as does expression level (all 3 correlated) #bg2011

2011-05-13 11:33:49
Brendan Maher @bmaher

TD: chaperone sequence evo correlates with protein expression #bg2011

2011-05-13 11:33:56
National Human Genome Research Institute @genome_gov

Pavel Tomancak: "Gene expression divergence recapitulates the develpomental hourglass" #bg2011

2011-05-13 11:37:55
Luke Ward @Luke__Ward

PT: Darwins expln for the similarity of fetuses x-species - the fetus is shielded from the environment, #bg2011

2011-05-13 11:43:31
Luke Ward @Luke__Ward

PT: morphology starts divergent,similar @ phylotypic stage of devel,then diverges again. Does expression go through hourglass too? #bg2011

2011-05-13 11:46:20
National Human Genome Research Institute @genome_gov

PT: variation in expression is higher 'early' and 'late' in development than in 'middle'; similar to morphology #bg2011

2011-05-13 11:50:26
Luke Ward @Luke__Ward

PT: Yes, especially body patterning genes #bg2011

2011-05-13 11:50:42
National Human Genome Research Institute @genome_gov

PT: evidence of stabilizing selection in maintenance of the pattern of expression variation #bg2011

2011-05-13 11:53:12
Mike Lin @nilekim

Glad I stayed for Pavel Tomancak's wonderful late-nite #bg2011 talk on gene expression recapitulating the developmental hourglass!

2011-05-13 11:53:50
National Human Genome Research Institute @genome_gov

PT: ancient genes of multicellularity are expressed at the least divergent stage of development #bg2011

2011-05-13 11:55:02
Luke Ward @Luke__Ward

PT: Also genes expressed at the phylotypic stage are evolutionarily more ancient #bg2011

2011-05-13 11:55:20
BGI Group @TheBgiGroup

Yay! RT @lukejostins: KB: Which assembly was best? Everyone is a winner but SOAPdenovo, ALLPATHS and SGA were more winners than most #BG2011

2011-05-13 13:11:27
Shane McKee @shanemuk

Call THAT a title?!?! :-) “@dgmacarthur: Aoife McLysaght (@aoifemcl) ancient duplicated genes and human disease. #bg2011

2011-05-13 15:54:12
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