放射線被ばくの既往がある人に積極的な検査・治療を勧める理由

kazu @Kazu031104

Mihailescu DV, Schneider AB (2008) "Size, Number, and Distribution of Thyroid Nodules and the Risk of Malignancy .." http://t.co/AAbxMWCm5P

kazu @Kazu031104

Mihailescu DV (2008) http://t.co/AAbxMWCm5P Schneiderと共著論文．Michael Reese Hospital でのコホート研究。1974からスクリーニングを開始。全例に対して触診と画像診断を含むスクリーニングを行った。

kazu @Kazu031104

画像診断としては、初期は甲状腺シンチを用い、1993年以降は超音波検査を用いた。@Kazu031104

kazu @Kazu031104

Mihailescu (2008) 甲状腺結節の大きさで区分した場合の結節に対する甲状腺がんの割合、https://t.co/OcC18tt45B 0.5cm以上に関しては有意差はない @Kazu031104

kazu @Kazu031104

Mihailescu (2008): FIG. 1. Prevalence of thyroid cancer as a function of nodule size. http://t.co/WXj5L9dTNE

拡大

kazu @Kazu031104

@myen Mihailescu (2008): FIG. 2. Cancer size by rank order of the largest cancer. http://t.co/Xlo11teQCa

拡大

kazu @Kazu031104

@myen Mihailescu (2008): TABLE 2. Frequency of thyroid cancer in patients with single and multiple nodules http://t.co/teCR27ttB6

拡大

kazu @Kazu031104

Bucci A, Schneider AB (2001) "Behavior of Small Thyroid Cancers Found by Screening Radiation-Exposed Individuals" http://t.co/f4HyIID5NK

kazu @Kazu031104

Bucci A. (2001) http://t.co/Ajvzfv5T3Z Schneiderとの共著論文。Michael Reese Hospitalでのホコート研究 @Kazu031104

kazu @Kazu031104

Bucci (2001) ルーチンとスクリーニングとで見るかる甲状腺がんの大きさの比較 https://t.co/7ZPuorFvfR スクリーングで見るかる甲状腺がんの50％以上は10mm以下の大きさ @Kazu031104

kazu @Kazu031104

@myen Bucci A (2001): TABLE 1. Characteristics of thyroid cancers detected by routine care and by screening http://t.co/5h1yIZkFAj

拡大

kazu @Kazu031104

@myen Bucci (2001:) FIG. 1. Frequency histogram of the sizes of the thyroid cancers .. http://t.co/0ax6SjUSbU

拡大

kazu @Kazu031104

@myen Bucci (2001): FIG. 2. Recurrence-free survival in patients whose thyroid cancers ... http://t.co/CZi5grzpM0

拡大

kazu @Kazu031104

@myen Bucci (2001): FIG. 3. Recurrences of thyroid cancer according to the size of the original cancer http://t.co/5W1LQzDOZd

拡大

kazu @Kazu031104

@myen Bucci (2001): TABLE 2. Comparison of the characteristics of the subjects with small (<10 mm) thyroid cancers http://t.co/PV6mrsPeBa

拡大

kazu @Kazu031104

@myen Bucci (2001): TABLE 4. Relative risks for recurrence of thyroid cancers by cancer size at initial diagnosis http://t.co/QudVwOh7Gz

拡大

kazu @Kazu031104

@myen Bucci (2001): "1) The increased risk of recurrence associated with short latency may be a marker of younger age at diagnosis ..."

kazu @Kazu031104

@myen Bucci (2001) "Short latency may also be an indicator of inherently faster growth and earlier metastasis"

kazu @Kazu031104

@myen Bucci (2001): "2) The presence of metastases in lymph nodes was a risk factors."

kazu @Kazu031104

@myen Bucci (2001) "3) The observation that multifocal involvement is a risk factor for recurrence has not been made previously."

kazu @Kazu031104

@myen Bucci (2001): "4) Why radiation dose is associated with increased risk of recurrence of small thyroid cancers ... is not clear."

kazu @Kazu031104

Bucci A (2001) ".. thyroid screening of irradiated individuals identifies many small thyroid cancers associated with a very good prognosis."

kazu @Kazu031104

Bucci A (2001): "To the extent that small cancers are included in the evaluation of a screening program, its benefits may be overestimated."