Jacob (2014) に関連して

Jacob P (2014) "Ultrasonography survey and thyroid cancer in the Fukushima Prefecture" から 参照文献のいくつかのまとめへのリンク
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Seiichi Ushikubo @sushikubo

@myenSU メモ:AR(s,e,a,D)は、ARR(s,e,a,D)を被ばく時年齢(e)から到達年齢(a)まで積分した数値

2014-01-15 13:40:38
Seiichi Ushikubo @sushikubo

@myensu メモ:Jacob P. (2014) Table 2とTable 3 ARは%

2014-01-15 14:08:55

incidenceとprevalence

Seiichi Ushikubo @sushikubo

@myenSU Jacob P. (2014) "Different definitions of prevalence are given in the literature. In the present paper, ..."

2014-01-15 13:10:35
Seiichi Ushikubo @sushikubo

@myensu Jacob P. (2014) "... ‘proportion of a population that has a disease at a specific point in time’ is used as a definition."

2014-01-15 13:11:53
Seiichi Ushikubo @sushikubo

@myenSU Jacob P. (2014) "... incidence rate is defined as number of new cases reported per year and per number of persons in the population"

2014-01-15 13:13:02
Seiichi Ushikubo @sushikubo

Jacob P. (2014) "the first campaign of the new programme of ultrasonography surveys yields the prevalence of thyroid cancer, .."

2014-01-17 10:31:06
Seiichi Ushikubo @sushikubo

Jacob P. (2014) ".. and subsequent campaigns the incidence rate among people who already participated in the first campaign." @sushikubo

2014-01-17 10:31:49

harvesting effect

Seiichi Ushikubo @sushikubo

@myensu Jacob P. (2014) harvesting effect "Early detection may lead to lower numbers of detected cases at later campaigns of a survey"

2014-01-15 14:03:39

screening factor

Seiichi Ushikubo @sushikubo

@myenSU Jacob P. (2014) Table 1 Expected prevalence of confirmed thyroid cancer among screened population groups http://t.co/kBrOF19B8E

2014-01-15 14:45:27
拡大
Seiichi Ushikubo @sushikubo

@myenSU Jacob P. (2014) Fig. 1 Increase in thyroid cancer incidence rate due to ultrasonography screening http://t.co/AqCLLTXaC5

2014-01-15 14:42:56
拡大
Seiichi Ushikubo @sushikubo

@myenSU Jacob P. (2014) Eq.1 P: prevalence λ: average incidence rates fsp: differences in the study protocols http://t.co/QNGccNedlT

2014-01-17 11:54:01
拡大
Seiichi Ushikubo @sushikubo

@myenSU Jacob P. (2014) "... prevalence ... is estimated by taking into account differences in study protocols and sex–age structures ..."

2014-01-17 12:09:20

Thyroid cancer incidence rate in the Fukushima Prefecture under the condition of continued ultrasonography surveys is estimated to be increased compared with the incidence rate in 2007 by a factor of 7.4, with a 95 % confidence range from 0.96 to 17.3.

Thyroid cancer incidence rate in the UkrAm cohort during the second to fourth screening is estimated to be higher than the national incidence rate in Ukraine by a factor, fUA, of 3.6, with a 95 % confidence range from 0.5 to 7.9

This choice is supported by the thyroid screening study in Hong Kong (Yuen et al. 2011), in which the ratio for nodules larger than 5 mm and larger than 10 mm is 2.4 (398/169). For tumours, the ratio is 2.2 (11/ 5), nearly equal to that for nodules.

The screenings from October 2011 to March 2013 in the Fukushima Prefecture detected 1,125 nodules larger than 5 mm and 354 nodules larger than 10 mm (Fukushima Medical University 2013b). Correspondingly, the upper boundary of fsp is estimated to be 1,125/354 = 3.2. The lower boundary is assumed to correspond to no additional cases according to differences in the study protocol, 1.0. The factor fsp is assumed to have a symmetrical triangular distribution between these two boundaries with a maximum at 2.1.

Seiichi Ushikubo @sushikubo

@myenSU Jacob P. (2014) Fig.1 補足説明(1) Likhtarov I. と Jacob P. は、全例の"systematic"ではなく、“diagnostic suspicion bias”のかかった集団から診断された患者、すなわち"grey"

2014-01-16 10:29:19
Seiichi Ushikubo @sushikubo

@myenSU Jacob P. (2014) Fig 1. 補足説明(2) UkrAm は全例に超音波検査を行った"systematic screening"。日本の場合と比較できる。ただし抽出条件が異なるため Screenig factor が異なる。

2014-01-16 10:33:14
Seiichi Ushikubo @sushikubo

@myensu 不思議に思うのは、"gray screening"であるLikhtarov/Jacobと”systematic screening"であるUkrAmとでscreening factorに差がないこと。その気になって触ると1cmは見つかるってことなのかな。

2014-01-16 10:56:06

ooooooooooooooooooooooooooooooo

この論文の大前提